TABLE 2

Cox proportional hazards models for prediction of all-cause mortality

Total population (n = 994)
No CHD (n = 742)
Possible or definite CHD (n = 252)
HR95% CIχ2PHR95% CIχ2PHR95% CIχ2P
Adjusted for study center only
 STD ≥50 μV4.683.12–7.0155.9<0.0015.082.46–10.5119.2<0.0012.981.77–5.0216.9<0.001
 PCA ratio*2.111.46–3.0515.7<0.0011.440.77–2.701.30.2591.881.15–3.096.20.013
 QTc >460 ms1.951.35–2.8312.6<0.0011.901.16–3.126.40.0111.821.05–3.174.50.033
Adjusted for multiple covariates
 STD ≥50 μV2.361.38–4.029.80.0022.871.05–1.124.20.0401.951.01–3.763.90.047
 PCA ratio*1.330.82–2.131.30.2461.080.49–2.380.10.8481.440.80–2.591.50.221
 QTc >460 ms2.031.32–3.1210.40.0012.191.25–3.817.60.0061.430.74–2.781.10.287
  • *

    * >32.0% in women, >24.6% in men.

  • Cox model with all three ECG variables entered, adjusted for age, BMI, diastolic and systolic blood pressures, fasting glucose, GHb, HDL and LDL cholesterol levels, triglyceride level, albuminuria, alcohol use, history of smoking, and study center. Prevalent CHD was included as a covariate only in the total population. HR, hazard ratio.