TABLE 3

Estimated parameters of the two-compartment minimal model before (pre) and after (16 h and 1 week) the training

Pre16 h1 week
V1 (dt/kg)0.90 ± 0.041.13 ± 0.06*1.13 ± 0.05*
k21 (min−1)0.1269 ± 0.00950.1083 ± 0.01360.1062 ± 0.0093
k12 (min−1)0.1387 ± 0.01860.1242 ± 0.01170.1212 ± 0.0085
k02 (min−1)0.00411 ± 0.000320.00444 ± 0.000510.00500 ± 0.00024
p2 (min−1)0.091 ± 0.0150.088 ± 0.0090.093 ± 0.007
sk (ml · μU−1 · min−1)0.00167 ± 0.000380.00244 ± 0.000610.00164 ± 0.00044
kp (min−1)0.0042 ± 0.00020.0041 ± 0.00020.0048 ± 0.0003
  • Values are the means ± SE. V1, volume of the first compartment; k21, k12, and K02, glucose kinetic parameters; p2 and sk parameters describing insulin action; kp, proportional effect of glucose mass in the first compartment on glucose disposal from the same compartment.

  • *

    * P < 0.05 vs. before training.