Comparison of potential regulators of VMN neuronal glucosensing with regard to responsiveness or nonresponsiveness to 4 mmol/l alloxan and expression of potential regulators of glucosensing
GK | GK(+) GLUT2(+) | GK(−) GLUT2(+) | GKRP | HK-1 | |
---|---|---|---|---|---|
GE | |||||
Alloxan(+) | 76 (28/37) | 30 (6/20) | 38 (3/8) | 9 (1/11) | 87 (33/38) |
Alloxan(−) | 45 (9/20) | 0 (0/7) | 45 (5/11) | 11 (1/9) | 100 (9/9) |
GI | |||||
Alloxan(+) | 74 (14/19) | 17 (2/12) | 40 (2/5) | 0 (0/5) | 92 (11/12) |
Alloxan(−) | 18 (2/11) | 0 (0/2) | 25 (2/8) | 0 (0/7) | 90 (19/21) |
Data are percent, with number of neurons identified over the total number examined given in parentheses.