TABLE 1

HSL activity and TG content in BAT of cold-exposed mice

MouseHours at 4°CHSL (nmol FFA · min−1 · mg protein−1)TG (mg/IBAT × 10−1)
WT
05.0 ± 0.92.5 ± 0.5
69.4 ± 1.23.0 ± 0.3
247.8 ± 1.11.0 ± 0.2*
Dio2−/−
04.8 ± 0.63.5 ± 1.0
613.9 ± 2.0*1.3 ± 0.4*
2415.2 ± 2.6*0.5 ± 0.2*
Hypothyroid
06.3 ± 1.32.0 ± 0.8
612.4 ± 1.90.3 ± 0.3*
  • Data are means ± SD of four to five animals.

  • *

    * P < 0.001 vs. the same time in WT animals;

  • P < 0.01 vs. the same time in WT animals by ANOVA. Hypothyroid mice are WT. This experiment was performed twice.