TABLE 1

Donor information and islet isolation results

ControlType 2 diabetes
n1414
Donor age (years)51 ± 853 ± 8
Donor weight (kg)90 ± 2297 ± 28
BMI (kg/m2)31 ± 732 ± 9
Blood glucose at admission (mg/dl)194 ± 120336 ± 171*
Cold ischemia time (min)417 ± 130398 ± 110
Pancreas weight (g)101 ± 31104 ± 37
Total digestion time (min)63 ± 1662 ± 12
First-phase digestion time (min)21 ± 623 ± 6
Islet no. postdigestion414,571 ± 127,993232,173 ± 92,567
Islet IEq postdigestion597,569 ± 216,602256,260 ± 162,575
Islet IEq/g postdigestion6,037 ± 2,2222,588 ± 1,526
Islet no. postpurification287,573 ± 95,588133,558 ± 45,927
Islet IEq postpurification436,049 ± 158,544175,128 ± 82,114
Islet IEq/g postpurification5,359 ± 3,3521,772 ± 933
Islet recovery rate73%68%
Islet purity (%)76 ± 2073 ± 17
Insulin/protein4,677 ± 3,3108,049 ± 4,446
Amylase/protein0.09 ± 0.130.12 ± 0.13
  • Data are means ± SD.

  • *

    * P < 0.05;

  • P < 0.001.