Markers with evidence for linkage (P ≤ 0.001) in the 10-cM genome scan
| Positive markers | Interval* | Position† (cM) | Traits | MLB LOD (P)‡ | MLS LOD (P)‡ | PCORR§ | PUNCORR§ | 1-LOD unit (CI) (cM) |
|---|---|---|---|---|---|---|---|---|
| D2S325 | 2q35 | 215.26 | PCT99 | 2.77 (0.0002) | 3.26 (0.0001) | 0.16 | 0.08 | 20.83 (222.1–242.9) |
| D6S287 | 6q22.31 | 124.49 | PCT97 | 3.61 (0.00002) | 4.29 (0.000009) | 0.01 | 0.01 | 17.03 (128.2–145.2) |
| D6S287 | 6q22.31 | 124.49 | PCT95 | 3.08 (0.00008) | 3.62 (0.00005) | 0.08 | 0.06 | 17.03 (128.2–145.2) |
| D6S287 | 6q22.31 | 124.49 | PCT99 | 2.07 (0.001) | 2.33 (0.001) | 0.45 | 0.37 | 29.00 (125.3–154.3) |
| D15S1007 | 15q14 | 26.78 | AAR | 2.11 (0.0009) | NA | 0.73 | 0.34 | 17.83 (23.9–41.8) |
| D16S516 | 16q23.1 | 112.09 | AAR | 2.08 (0.001) | NA | 0.74 | 0.35 | 31.43 (87.78–119.21) |
| D19S226 | 19p13.12 | 43.34 | AAR | 2.08 (0.001) | NA | 0.74 | 0.35 | 23.58 (26.2–49.8) |
* Chromosomes locations were determined from the map available in the Human Genome Browser.
† Haldane’s distances were used to determine the locations of linkage peaks.
‡ P: single-test P value;
§ PCORR: empirical genome-wide P value when considering all the traits; PUNCORR: empirical genome-wide P value when considering one trait only. NA, not available. A Genethon map was used.