Multipoint results after the fine-mapping step
| Chromosome | Fine-mapping interval (cM) | Average density | Trait | MLB LOD (P)* | MLS LOD (P)* | 1-LOD unit (CI) (cM) | Location (cM) |
|---|---|---|---|---|---|---|---|
| 2q33.2-q36.3 | D2S112-D2S396 | 3.84 | PCT99 | 2.73 (0.0002) | 3.05 (0.0002) | 22.34 (214.96–237.30) | 230.62 |
| PCT97 | 2.08 (0.001) | 2.33 (0.001) | 24.46 (214.00–238.46) | 230.62 | |||
| 6q22.31-q23.2 | D6S462-D6S441 | 3.01 | PCT97 | 3.27 (0.00005) | 4.06 (0.00002) | 10.85 (125.97–136.82) | 129.76 |
| PCT95 | 3.13 (0.00007) | 3.77 (0.00003) | 11.53 (125.29–136.82) | 128.95 | |||
| 15q12-q15.1 | D15S128-D15S153 | 2.22 | AAR | 2.53 (0.0003) | NA | 13.67 (21.71–35.38) | 32.69 |
| 16q22.1-q24.1 | D16S415-D16S520 | 3.13 | AAR | 2.54 (0.0003) | NA | 21.68 (95.63–117.31) | 105.15 |
| 17p13 | D17S849-D17S799 | 1.96 | PCT95 | 2.25 (0.0007) | 2.35 (0.001) | 6.50 (16.59–23.09) | 18.70 |
| 19p13.3p13.11 | D19S221-D19S414 | 2.58 | AAR | 2.13 (0.0009) | NA | 22.62 (24.71–47.33) | 44.60 |
* P: single-test P value. A Genethon map was used. Only the traits with suggestive evidence for linkage are reported here (LOD MLS ≥2.32, LOD MLB ≥2.08, P ≤ 0.001).