TABLE 2

Metabolic parameters during hyperinsulinemic-euglycemic clamp periods in control (saline), IL-6–treated, IL-6–and IL-10–co-treated, lipid-infused, and lipid- and IL-10–co-treated groups

Clamp period
Plasma glucose (mmol/l)Plasma insulin (pmol/l)Glucose infusion rate (μmol · kg−1 · min−1)
Control7.1 ± 0.2409 ± 22183 ± 11
IL-6–treated7.0 ± 0.7432 ± 5288 ± 12*
IL-6–and IL-10–co-treated7.1 ± 0.4420 ± 16191 ± 14
Lipid-infused6.4 ± 0.2427 ± 56140 ± 6*
Lipid- and IL-10–co-treated6.6 ± 0.4442 ± 61180 ± 17
  • Data are means ± SE.

  • *

    * P < 0.05 vs. control mice by Duncan’s multiple range test.