TABLE 3

Skeletal muscle ceramide content (nmol/g tissue) at baseline, after 4-h hyperinsulinemia, and after clamp with Intralipid/heparin infusion (n = 10)

Fatty acidBaselineAfter 4-h clampAfter 4-h clamp with Intralipid/ heparin infusion
n101010
Total437.66 ± 263.50423.76 ± 130.67646.89 ± 311.43*
Myristic (14:0)38.16 ± 11.7443.70 ± 29.4155.53 ± 30.24
Palmitic (16:0)133.30 ± 81.94145.38 ± 48.68209.64 ± 95.81*
Palmitoleic (16:1)9.78 ± 8.378.47 ± 4.2410.34 ± 6.49
Stearic (18:0)96.47 ± 69.6997.61 ± 43.68149.52 ± 105.59*
Oleic (18:1)74.39 ± 60.6553.70 ± 42.3392.48 ± 66.64
Linoleic (18:2)20.92 ± 16.3413.15 ± 7.3428.52 ± 20.09*
Linolenic (18:3)5.58 ± 4.974.93 ± 2.648.92 ± 4.45*
Arachidic (20:0)7.66 ± 6.117.36 ± 4.289.96 ± 5.94
Arachidonic (20:4)7.42 ± 7.985.88 ± 5.976.07 ± 8.41
Eicosapentaenoic (20:5)2.43 ± 2.123.91 ± 2.714.99 ± 1.78*
Behenic (22:0)12.01 ± 10.0613.32 ± 9.4121.94 ± 11.62*
Docosahexaenoic (22:6)3.55 ± 3.453.64 ± 3.649.43 ± 4.66*
Nervonic (24:1)25.98 ± 16.1022.70 ± 13.4139.56 ± 20.68*
  • Data are expressed as means ± SD.

  • *

    * P < 0.05 in comparison to baseline values.