TABLE 4

Effects of 7 days of diet and glucose feeding on [3H]NE turnover in male rats

Diet50Diet100GlucoseP
n212421
Body wt (g)204.9 ± 1.5a236.0 ± 1.9b217.8 ± 2.0c<0.0001
IBAT
 Tissue wt (mg)206 ± 5a234 ± 5b336 ± 12c<0.0001
 Tissue NE (ng)800 ± 20a821 ± 17a729 ± 16b0.001
 Fractional NE turnover (%/h)5.4 ± 0.8a7.5 ± 0.8a12.5 ± 0.9b<0.0001
 Total NE turnover (ng/h)43.6 ± 7.6a61.9 ± 7.4b91.2 ± 8.5c<0.05
Retroperitoneal fat
 Tissue wt (mg)151 ± 12a350 ± 24b367 ± 24b<0.0001
 Tissue NE (ng)55.6 ± 2.7a,b61.0 ± 2.0a51.1 ± 2.0b0.009
 Fractional NE turnover (%/h)5.4 ± 0.9a9.0 ± 0.7b9.0 ± 0.7b0.001
 Total NE turnover (ng/h)2.99 ± 0.63a5.52 ± 0.59b4.62 ± 0.55b<0.05
Epididymal fat
 Tissue wt (mg)492 ± 20a744 ± 24b779 ± 23b<0.0001
 Tissue NE (ng)50.1 ± 1.9a46.0 ± 1.2a,b43.8 ± 1.7b0.028
 Fractional NE turnover (%/h)3.2 ± 0.63.4 ± 0.54.1 ± 0.4NS
 Total NE turnover (ng/h)1.61 ± 0.341.55 ± 0.281.81 ± 0.23NS
  • Data are means ± SE. “Diet50” refers to animals fed 50% of energy intake consumed by “Diet100” and glucose groups. Variables with the same superscript are not statistically different; those with dissimilar superscripts differ significantly by post hoc analysis at P < 0.05.