TABLE 2

TF-dependent PCA of cultured duct cells in whole blood

Duct cell number*Anti-TFClotPlatelets (×103/μl)Fibrinogen (mg/dl)
00/7196 ± 15.9246 ± 14.2
1020/3173 ± 31.1251 ± 21.0
1035/59 ± 4.2<20
+0/3154 ± 22.3214 ± 32.2
  • Data are means ± SE.

  • *

    * Cultured primary duct cells (102 or 103 cells) were added to 5 ml whole blood incubated in tubing loops under agitation at 37°C. When indicated, duct cells were pretreated with anti-TF antibody. Clot formation, platelet counts, and fibrinogen levels were monitored after 30 min incubation in the absence or presence of duct cells;

  • number of clotted samples/number of experiments.