TABLE 5

LD estimates between markers close to ISL1 and PAX4 in 196 Swedish type 1 diabetic families

Marker 1Marker 2Distance between markers (kb)No.dfχ2P value (<)D′
Chromosome 5p11-q13
D5S430ISL1:19,657600313.30.0040.32
D5S822ISL1:11686014347.60.00010.97
D5S822ISL1:2177605497.20.00010.39
D5S822ISL1:31786084116.40.00010.43
D5S822ISL1:4179382462.40.00010.40
D5S822ISL1:5169567410.20.040.84
D5S822ISL1:61695454110.80.00010.79
ISL1:1ISL1:29.1593145.80.00011.00
ISL1:1ISL1:39.3596140.70.00010.95
ISL1:1ISL1:411376119.50.00010.83
ISL1:5ISL1:70.02545197.50.00011.00
ISL1:6ISL1:70.02548133.50.00011.00
ISL1:6ISL1:28.2538116.20.00010.61
ISL1:6ISL1:38.5535118.60.00010.65
ISL1:6ISL1:49.8426123.80.00010.85
ISL1:2ISL1:30.36001476.40.00010.90
ISL1:2ISL1:41.63771299.80.00010.89
ISL1:3ISL1:41.33771325.80.00010.94
Chromosome 7q32
CFTRPAX4:110,12860938.10.050.12
PAX4:1PAX4:215571371.10.00010.82
PAX4:1PAX4:34639180.10.00010.94
PAX4:1D7S5302,851613410.20.040.16
PAX4:2PAX4:33611170.50.00010.89
  • Only combinations of markers that show significant evidence of LD (P < 0.05) are shown.