TABLE 4

Parameters for glucose clamp studies in C57B/6J mice

PBSInsulin euglycemiaInsulin hyperglycemia
Body weight (g)27 ± 1.026.3 ± 0.827.8 ± 1.1
Basal glucose (mg/dl)132 ± 11.1129 ± 8.3134 ± 11.1
Basal insulin (ng/ml)1.1 ± 0.20.98 ± 0.140.96 ± 0.31
Clamp glucose (mg/dl)131 ± 4.8129 ± 2.1336 ± 4.0*
Clamp insulin (ng/ml)0.9 ± 0.1299 ± 46.7315 ± 36
Glucose infusion (mg · kg–1 · min–1)96.4 ± 4.8137 ± 9.6
  • Data are means ± SE, n = 5. Male C57BL/6J mice (12 weeks) were subjected to hyperinsulinemic-euglycemic or hyperglycemic clamps. Control mice received PBS infusion.

  • *

    * P < 0.05 vs. PBS;

  • P < 0.05 vs. euglycemia.