TABLE 1

Metabolic parameters for all groups at week 20

ParametersControlDiabetesDiabetes + ALT-711Diabetes + AG
n20202020
GHb (%)3.8 ± 0.113.6 ± 0.4*14.1 ± 1.2*11.9 ± 0.5*
Body weight (g)30.0 ± 0.521.1 ± 0.3*22.0 ± 1.0*21.0 ± 0.3*
Systolic blood pressure (mmHg)117 ± 2118 ± 5104 ± 4§125 ± 6
Total cholesterol (mmol/l)14.2 ± 0.535.6 ± 2.4*22.0 ± 3.6*§31.6 ± 1.2*
HDL cholesterol (mmol/l)4.5 ± 0.28.2 ± 0.7*7.5 ± 1.1*6.5 ± 0.3*§
LDL cholesterol (mmol/l)9.2 ± 0.326.1 ± 1.5*13.9 ± 2.4§24.1 ± 0.7*
Triglycerides (mmol/l)0.9 ± 0.11.9 ± 0.3*1.2 ± 0.32.0 ± 0.3*
  • Data are means ± SE except for GHb and body weight, which are means ± SD.

  • *

    * P < 0.001 vs. control group;

  • P < 0.05 vs. diabetic group;

  • P < 0.001 vs. diabetes + ALT group;

  • §

    § P < 0.001 vs. diabetic group.