TABLE 1

Serum parameters measured in the ad libitum–fed state in transgenic hyperresistinemic mice and their wild-type littermate controls at 8–11 weeks of age

Wild-typeHyperresistinemic
Body weight (g)24 ± 0.524.1 ± 0.6
Glucose (mg/dl)180.1 ± 9.2185.1 ± 7.6
Free fatty acid (mEq/l)0.66 ± 0.030.67 ± 0.03
Triglycerides (mg/dl)190 ± 21188 ± 17
Insulin (ng/ml)0.95 ± 0.170.89 ± 0.19
Leptin (ng/ml)2.86 ± 0.222.55 ± 0.30
AST (units/l)12.9 ± 0.813.4 ± 1
ALT (units/l)9.0 ± 0.69.4 ± 0.7
Adiponectin (μg/ml)5.7 ± 0.45.9 ± 0.5
Body fat (%)11.9 ± 0.711.3 ± 0.7
  • Data are means ± SE. For serum measurements, n = 10 for wild-type and n = 11 for transgenic. For body fat determination, n = 9 (wild-type) and n = 11 (transgenic). ALT, alanine aminotransferase; AST, aspartate aminotransferase.