TABLE 1

Plasma parameters in overnight-fasted mice that received an intravenous infusion of PYY or vehicle under basal or hyperinsulinemic conditions

Basal
Hyperinsulinemic
VehiclePYYVehiclePYY
Glucose (mmol/l)4.9 ± 0.65.0 ± 0.69.0 ± 0.99.2 ± 2.0
FFAs (mmol/l)0.9 ± 0.21.0 ± 0.20.4 ± 0.10.5 ± 0.1
Insulin (ng/ml)0.3 ± 0.10.3 ± 0.15.2 ± 2.96.7 ± 2.7
PYY3–36 (pg/μl)<13.8 ± 0.7< 13.2 ± 0.7
  • Data are the means ± SD for at least seven mice per group.