TABLE 2

Messenger RNA levels of leptin, TNF-α, IL-6 and -8, adiponectin, and PAI-1 before and after the diet

Moderate fat (n = 17)
Low fat (n = 17)
Total
BeforeAfterPBeforeAfterPBeforeAfterP
Leptin (10−3 AU)1.54 ± 0.321.18 ± 0.270.00031.99 ± 0.341.68 ± 0.290.0761.77 ± 0.231.43 ± 0.200.0004
TNF-α (10−7 AU)3.42 ± 0.303.19 ± 0.290.493.02 ± 0.203.11 ± 0.410.693.22 ± 0.183.15 ± 0.250.47
IL-6 (10−8 AU)6.07 ± 0.943.69 ± 0.390.0134.89 ± 0.633.36 ± 0.450.0285.48 ± 0.573.53 ± 0.300.0011
IL-8 (10−7 AU)5.42 ± 1.15.16 ± 0.810.834.10 ± 0.573.95 ± 0.560.804.76 ± 0.634.56 ± 0.500.50
Adiponectin (10−3 AU)3.31 ± 0.443.03 ± 0.340.182.85 ± 0.482.67 ± 0.470.463.08 ± 0.322.85 ± 0.290.15
PAI-1 (10−6 AU)3.74 ± 0.634.26 ± 1.40.232.42 ± 0.382.33 ± 0.550.463.08 ± 0.383.29 ± 0.760.16
  • Values are means ± SE (Wilcoxon’s signed-rank test). Messenger RNA values are expressed relative to the reference gene 18S.