TABLE 4

Circulating levels of leptin, TNF-α, IL-6, and adiponectin and PAI-1 activity before and after the diet

Moderate fat (n = 20)
Low fat (n = 20)
Total
BeforeAfterPBeforeAfterPBeforeAfterP
Serum leptin (ng/ml)38.8 ± 3.129.9 ± 2.60.008036.5 ± 4.024.4 ± 2.50.001237.6 ± 2.527.2 ± 1.8<0.0001
Plasma TNF-α (pg/ml)4.80 ± 1.64.84 ± 1.50.652.79 ± 0.722.16 ± 0.530.0593.79 ± 0.873.50 ± 0.790.56
Plasma IL-6 (pg/ml)3.82 ± 0.413.54 ± 0.480.0643.56 ± 0.223.38 ± 0.370.313.69 ± 0.233.46 ± 0.300.046
Serum adiponectin (μg/ml)16.4 ± 1.716.9 ± 1.60.8818.3 ± 1.820.6 ± 1.90.3017.3 ± 1.318.7 ± 1.30.40
Plasma PAI-1 (IU/ml)28.6 ± 4.119.4 ± 4.10.001627.0 ± 4.114.2 ± 3.1<0.000127.8 ± 2.916.8 ± 2.6<0.0001
  • Values are means ± SE (Wilcoxon’s signed-rank test).