TABLE 1

Baseline characteristics of subjects

NGT
IFG alone
IGT alone
IFG + IGT
P
ADA*ModifiedADA*ModifiedADAModifiedADAModifiedADAModified
n (%)398 (42.5)232 (24.7)33 (3.5)199 (21.2)378 (40.3)153 (16.3)128 (13.7)353 (37.8)
Age (years)48.2 ± 0.8648.1 ± 1.1649.2 ± 2.6348.6 ± 1.1457.4 ± 0.8658.4 ± 1.4557.6 ± 1.2757.9 ± 0.82
Men (%)46.239.284.860.861.448.480.573.9
FPG (mmol/l)93.5 ± 0.3291.2 ± 0.41101.2 ± 1.1197.5 ± 0.4495.3 ± 0.3392.1 ± 0.50103.1 ± 0.5799.7 ± 0.34<0.0001<0.0001
2-hPG (mmol/l)103.9 ± 1.27104.1 ± 1.66108.7 ± 4.37104.5 ± 1.79131.5 ± 1.31128.7 ± 2.02137.6 ± 2.26135.0 ± 1.40<0.0001<0.0001
BMI (kg/m2)23.7 ± 0.1723.3 ± 0.2224.1 ± 0.5824.2 ± 0.2325.0 ± 0.1724.1 ± 0.2626.2 ± 0.3025.9 ± 0.18<0.0001<0.0001
Waist circumference80.8 ± 0.4279.9 ± 0.5580.2 ± 1.4581.8 ± 0.5983.3 ± 0.4481.0 ± 0.6787.8 ± 0.7586.1 ± 0.46<0.0001<0.0001
Systolic blood pressure122.2 ± 0.85122.2 ± 1.11126.6 ± 2.91123.1 ± 1.19126.4 ± 0.87124.6 ± 1.35125.0 ± 1.51126.8 ± 0.930.00820.0098
Diastolic blood pressure76.6 ± 0.5376.2 ± 0.6979.4 ± 1.8177.6 ± 0.7479.6 ± 0.5478.0 ± 0.8479.7 ± 0.9480.4 ± 0.580.0007<0.0001
Triglycerides (mg/dl)73.370.673.176.488.985.793.892.3<0.0001<0.0001
    (95% CI)(69.9–76.8)(66.4–75.2)(61.8–86.5)(71.5–81.7)(84.6–93.3)(79.4–92.3)(86.1–102.0)(87.6–97.3)
HDL cholesterol (mg/dl)49.9 ± 0.6450.1 ± 0.8451.4 ± 2.0950.0 ± 0.8848.5 ± 0.6649.9 ± 1.0346.2 ± 1.1147.0 ± 0.690.01950.0105
LDL cholesterol (mg/dl)115.6 ± 2.07113.7 ± 2.68113.5 ± 6.63117.5 ± 2.92113.9 ± 2.32114.7 ± 3.34117.7 ± 3.99115.1 ± 2.540.83750.8109
Smokers (%)21.423.315.218.118.719.717.517.60.71370.4965
Mean ATP III MetS score1.2 ± 0.051.1 ± 0.061.3 ± 0.161.2 ± 0.072.0 ± 0.051.7 ± 0.072.3 ± 0.082.2 ± 0.05<0.0001<0.0001
Mean FRS9.5 ± 0.209.4 ± 0.269.5 ± 0.659.6 ± 0.2810.1 ± 0.2110.0 ± 0.3211.0 ± 0.3510.5 ± 0.220.00310.0136
CHD events/1,000 person-years5.95.93.45.46.46.46.16.30.80.95
  • Data are means ± SE, unless otherwise noted.

  • *

    * 1997 ADA criteria for IFG, with a cut point of 6.1 mmol/l;

  • criteria using a lower cut point for IFG of 5.5 mmol/l;

  • ANCOVA with 3 degrees of freedom and adjusted for age and sex. (See research design and methods for details.)