Expansion of dendritic cell subsets in the spleen and their expression of maturation markers after one 10-day course of Flt3-ligand in vivo
| Cell number (×10−6) | Fold increase | I-A+ (%) | CD80+ (%) | CD86+ (%) | |
|---|---|---|---|---|---|
| mDC | |||||
| No Flt3-ligand | 8.84 ± 0.8 | — | 81.9 ± 0.81 | 64.8 ± 2.8 | 41.7 ± 1.3 |
| +Flt3-ligand | 114 ± 28.9 | 12.9 | 51.9 ± 1.04 | 66.7 ± 4.7 | 51.5 ± 5.9 |
| pDC | |||||
| No Flt3-ligand | 4.96 ± 1.37 | — | 95.8 ± 0.98 | 34.8 ± 6.3 | 52.2 ± 2.4 |
| +Flt3-ligand | 29.0 ± 5.27 | 5.8 | 91.0 ± 1.39 | 52.9 ± 1.4 | 27.2 ± 0.8 |
Data are average ± SD.