TABLE 1

Coexpression of activins and activin receptors with insulin-, glucagon-, and cytokeratin-positive cells in the pancreas of NOD and IFN-γ transgenic mice

LigandsNOD
IFN-γ
InsulinGlucagonCKInsulinGlucagonCK
βA subunit+++/−++
βB subunit++++++
Type II receptor+++++
Type IIB receptor+/−+/−++
Type IB receptor+/−++
  • Pancreatic sections from NOD and IFN-γ transgenic mice were double stained with antibodies against βA and βB subunits; type II, type IIB, and type IB activin receptors; and insulin, glucagon, or cytokeratin (CK) antibodies. −, no coexpression; +/−, rarely co-expressed; +, coexpressed.