TABLE 1

Serum metabolites in wild-type and ob/ob mice obtained at 5:00 a.m. (peak fed) and 6 h after food removal (postabsorptive)

Wild-type peak fedOb/ob peak fedWild-type postabsorptiveOb/ob postabsorptive
Serum insulin (nmol/l)0.071 ± 0.016 (9)1.586 ± 0.317 (9)*0.03 ± 0.009 (9)0.569 ± 0.149 (9)
Serum triglycerides (mmol/l)3.998 ± 0.353 (9)8.051 ± 1.413 (9)*0.875 ± 0.105 (9)0.966 ± 0.245 (9)
Serum FFAs (mmol/l)1.387 ± 0.154 (9)2.618 ± 0.171 (10)*0.601 ± 0.079 (9)1.273 ± 0.105 (10)
  • Data are means ± SE (no. of samples).

  • *

    * P < 0.0005 vs. wild-type peak fed;

  • P < 0.04 vs. wild-type postabsorptive;

  • P < 0.04 vs. postabsorptive of the same genotype.