TABLE 1

Body weight, kidney weight, and blood glucose concentration

GroupBody wt (g)Kidney wt (mg)Blood glucose (mmol/l)
Nondiabetic26.3 ± 0.6288.7 ± 11.17.3 ± 0.4
Diabetic (vehicle)21.5 ± 1.0*293.2 ± 4.825.4 ± 3.1*
Diabetic (ES, 1 mg/kg)22.1 ± 0.6*269.4 ± 20.725.0 ± 1.8*
Diabetic (ES, 5 mg/kg)21.4 ± 1.1*228.7 ± 6.5*25.6 ± 2.5*
  • Data are means ± SE, n = 5 in each group. Vehicle was buffer treated. ES, endostatin peptide treated.

  • *

    * P < 0.05 vs. nondiabetic animals.

  • P < 0.01 vs. vehicle.

  • P < 0.05 vs. mice treated with endostatin peptide (1 mg/kg).