TABLE 1

Concentrations of liver markers in nondiabetic subjects with and without NCEP-defined metabolic syndrome and its components at the baseline IRAS examination

VariableAST (units/l)ALT (units/l)AST-to-ALT ratio (units/l)ALK (units/l)Bilirubin (mg/dl)CRP (mg/l)
All subjects (n)864864864859845865
    NCEP metabolic syndromeNo20.9815.551.3460.560.481.46
Yes22.84*19.601.1763.640.512.78
    Fasting hyperglycemiaNo21.2215.801.3461.010.481.63
Yes22.6420.471.1062.990.472.27*
    Abdominal obesityNo20.9115.441.3559.980.481.36
Yes22.81*19.441.1764.77§0.493.05
    Elevated triglycerideNo21.1216.091.3161.340.471.58
Yes22.2517.651.2661.440.512.15
    Reduced HDLNo21.5215.691.3759.440.471.50
Yes21.3817.43*1.2263.33*0.501.98§
    HypertensionNo20.7215.841.3060.600.471.43
Yes22.37*17.371.2962.240.502.14
Excluding former and heavy drinkers (n)701701701696682702
    NCEP metabolic syndromeNo20.6715.491.3359.670.481.41
Yes23.5720.571.1563.86*0.522.79
    Fasting hyperglycemiaNo21.1715.891.3360.360.491.60
Yes22.5621.071.0762.530.482.22*
    Abdominal obesityNo20.6915.391.3459.450.491.32
Yes23.32§20.511.1464.07*0.503.15
    Elevated triglycerideNo20.9416.161.2960.620.471.53
Yes22.5218.061.2561.340.522.12§
    Reduced HDLNo21.1215.721.3457.880.471.45
Yes21.7017.74*1.22*63.580.511.97§
    HypertensionNo20.5315.771.3060.300.471.40
Yes22.53*17.91*1.2661.280.502.09
  • Adjusted for age, sex, ethnicity, clinic.

  • * P < 0.01,

  • P < 0.0001,

  • P < 0.05,

  • § P < 0.001.