TABLE 4

Logistic regression analysis of markers of liver injury with risk of incident NCEP metabolic syndrome in IRAS subjects

Independent variableUnitOR (95% CI)
All subjects (n = 632)
    Log AST0.391.17 (0.97–1.41)
    Log ALT0.621.43 (1.15–1.77)*
    Log AST-to-ALT ratio0.480.72 (0.57–0.90)*
    Log ALK0.301.31 (1.06–1.61)
    Log total bilirubin0.461.12 (0.90–1.40)
    Log CRP1.081.33 (1.09–1.63)*
Excluding former and heavy drinkers (n = 512)
    Log AST0.371.15 (0.92–1.43)
    Log ALT0.591.41 (1.10–1.79)*
    Log AST-to-ALT ratio0.470.73 (0.57–0.95)
    Log ALK0.281.29 (1.02–1.64)
    Log total bilirubin0.461.09 (0.85–1.40)
    Log CRP1.091.29 (1.03–1.61)
  • Units reflect SDs of the baseline independent variable. OR (adjusted for age, sex, clinical center, ethnicity, and alcohol intake) refers to risk of incident metabolic syndrome associated with a 1-SD difference in the independent variable.

  • * P < 0.01,

  • P < 0.05.