Summary of multiple multivariate logistic regressions for retinopathy
Covariate effects from multiple models | df | χ2 | P value | R2 |
---|---|---|---|---|
Unadjusted effect | ||||
DCCT mean A1C | 1 | 34.3 | <0.0001 | 0.142 |
EDIC study mean A1C | 1 | 40.5 | <0.0001 | 0.168 |
Furosine, CML, pentosidine, fluorescence, acid/pepsin soluble | 6 | 62.2 | <0.0001 | 0.258 |
Pentosidine, fluorescence, acid/pepsin soluble | 4 | 21.8 | 0.0002 | 0.090 |
Furosine, CML | 2 | 59.4 | <0.0001 | 0.246 |
Furosine | 1 | 52.2 | <0.0001 | 0.216 |
CML | 1 | 27.7 | <0.0001 | 0.115 |
Adjusted effect | ||||
DCCT mean A1C effect adjusted for | ||||
Furosine, CML | 1 | 0.0 | 0.9874 | 0.000 |
Furosine | 1 | 0.4 | 0.5430 | 0.001 |
CML | 1 | 17.4 | <0.0001 | 0.072 |
EDIC study mean A1C effect adjusted for | ||||
Furosine, CML | 1 | 26.0 | <0.0001 | 0.108 |
Furosine | 1 | 24.6 | <0.0001 | 0.102 |
CML | 1 | 43.4 | <0.0001 | 0.180 |
Furosine, CML effect adjusted for | ||||
Pentosidine, fluorescence, acid/pepsin soluble | 2 | 46.3 | <0.0001 | 0.192 |
DCCT mean A1C | 2 | 32.7 | <0.0001 | 0.136 |
EDIC study mean A1C | 2 | 45.9 | <0.0001 | 0.190 |
Pentosidine, fluorescence, acid/pepsin soluble effect adjusted for | ||||
Furosine, CML | 4 | 4.8 | 0.3034 | 0.020 |
Furosine effect adjusted for | ||||
DCCT mean A1C | 1 | 22.2 | <0.0001 | 0.092 |
EDIC study mean A1C | 1 | 33.5 | <0.0001 | 0.139 |
CML effect adjusted for | ||||
DCCT mean A1C | 1 | 14.4 | <0.0001 | 0.061 |
EDIC study mean A1C | 1 | 27.6 | <0.0001 | 0.114 |
Dependent variable: three or more–step progression of retinopathy on the Early Treatment of Diabetic Retinopathy Scale or scatter laser therapy from DCCT close out through EDIC study year 10. As defined in the statistical methods section, χ2 and P values are from likelihood ratio test, and R2 is entropy R2.