TABLE 2

SAM, SAH, and hepatic SAM-to-SAH ratio

5 weeks11 weeks
ZDF fa/?ZDF fa/faZDF fa/?ZDF fa/fa
SAM88 ± 8.4a142.1 ± 11.3b172.9 ± 20.0a199.9 ± 15.5b
SAH12.3 ± 1.211.6 ± 1.311.9 ± 2.311.7 ± 2.2
SAM-to-SAH7.2 ± 0.7a12.3 ± 2.0b15.1 ± 4.717.5 ± 3.5
  • Data are means ± SD for six rats in each group, and values for SAM and SAH are expressed as nmol/g liver. At each age-group, differences in superscript letters indicate significant difference from the ZDF fa/? rats (P < 0.05).