TABLE 3

Genotype, allele, and haplotype distributions

tSNP*GenotypeTotalHardy-Weinberg testMAF (95% CI) (%)
111222χ2P
rs60674841,0937431261,9620.18NS25.4 (24.0–26.8)
rs18851776191,1094852,2130.03NS47.0 (45.5–48.5)
rs22821461,713286122,0110.22NS7.7 (6.9–8.6)
rs7180498139512822,0460.01NS37.0 (35.5–38.5)
rs37873485169984101,9241.37NS47.2 (45.7–48.8)
1484insG1,69718571,8893.82NS5.3 (4.6–6.0)
Haplotypers6067484rs1885177rs2282146rs718049rs37873481484insGFrequency (SE)
11111210.432 (0.0019)
22212110.242 (0.0016)
31111110.075 (0.0019)
41222110.073 (0.0015)
51211110.052 (0.0024)
61211120.052 (0.0017)
71212110.028 (0.0021)
81112210.016 (0.0010)
92211110.008 (0.0010)
  • * Includes one monozygotic and both dizygotic twins for each pair.

  • Tested in one of each monozygotic pair (one of each dizygotic pair and all singleton dizygotic twins).

  • Includes both dizygotic pairs and one of monozygotic pairs with genotype data on at least three tSNPs (n = 2,320).