Epidemiological studies showing an association between postprandial hyperglycemia with risk of CVD and mortality
| Hoorn Study | 2-h glucose better predictor of mortality than HbA1c | Ref. 9 |
| Honolulu Heart Program | 1-h glucose predicts coronary heart disease | Ref. 10 |
| Chicago Heart Study | 2-h postchallenge glucose predicts all-cause mortality | Ref. 11 |
| DECODE | High 2-h postload blood glucose is associated with increased risk of death, independent of fasting glucose | Ref. 12 |
| Coutinho et al. | 2-h glucose associated with CHD | Ref. 13 |
| Whitehall Study, Paris Prospective Study, and Helsinki Policemen Study | 2-h postchallenge glucose predicts all-cause and CHD mortality | Ref. 14 |
| Diabetes Intervention Study | Postmeal but not fasting glucose is associated with CHD | Ref. 15 |
CHD, coronary heart disease.