TABLE 1

Characteristics of Brazilian type 2 diabetic patients according to renal status

NormoalbuminuriaMicroalbuminuriaProteinuriaESRDP*
n529217160136
Male190 (35.9)106 (48.8)91 (56.9)80 (58.8)<0.001
Caucasian407 (76.9)159 (73.3)117 (73.1)97 (71.3)0.438
Age (years)58.3 ± 1058.9 ± 1160.1 ± 1060.2 ± 110.218
Duration of diabetes (years)9.8 ± 7.613.1 ± 9.815.1 ± 8.616.2 ± 8.2<0.001
BMI (kg/m2)28.7 ± 5.4528.8 ± 4.8430.1 ± 5.427.0 ± 4.17<0.001§
Waist-to-hip ratio0.94 ± 0.070.95 ± 0.080.97 ± 0.080.92 ± 0.120.061
Systolic blood pressure (mmHg)139 ± 23144 ± 24151 ± 25150 ± 22<0.001
Diastolic blood pressure (mmHg)86 ± 1388 ± 1388 ± 1683 ± 110.006§
Hypertension312 (59)162 (75)134 (84)116 (85)<0.001
Retinopathy (Absent/NPDR/PDR [%])70/24/0643/40/1720/41/3915/06/79<0.001
IHD123 (33.6)55 (39.3)57 (50.4)36 (54.5)0.001
A1C (%)6.67 ± 1.926.78 ± 2.046.67 ± 2.226.79 ± 1.960.736
Fasting plasma glucose (mg/dl)177 ± 69193 ± 97181 ± 83169 ± 830.453
Serum creatinine (mg/dl)0.91 (0.5–1.3)0.94 (0.4–1.2)1.3 (0.6–5.0)5.85 (2–18)
Total cholesterol (mg/dl)215 ± 46218 ± 47227 ± 53194 ± 46<0.001§
HDL cholesterol (mg/dl)45 ± 1243 ± 1242 ± 1242 ± 130.011
Triglycerides (mg/dl)144 (26–946)150 (43–1,470)192 (47–1,265)181 (59–900)<0.001#
A54T FABP2 genotypes (AA/AT/TT)292/213/24113/85/1978/68/1470/47/190.008
  • Data are means ± SD, median (range), or n (%) of cases.

  • * ANOVA, χ2, or Kruksal-Wallis test;

  • normoalbuminuria vs. all;

  • microalbuminuria vs. all;

  • § ESRD vs. all;

  • data available for 685 patients: normoalbuminuria, n = 366; microalbuminuria, n = 140; proteinurics, n = 113; and ESRD, n = 66;

  • normoalbuminuria vs. proteinuria and ESRD;

  • # proteinuria vs. all. NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.