TABLE 5

Changes in endothelial function between baseline and exit (12-month) visit

All
Type 1 diabetes
Type 2 diabetes
Vitamin EPlaceboVitamin EPlaceboVitamin EPlacebo
n323110132218
Brachial artery diameter (mm)
    Baseline3.78 ± 0.743.41 ± 0.603.46 ± 0.593.21 ± 0.523.93 ± 0.763.55 ± 0.63
    Exit3.97 ± 0.723.55 ± 0.683.59 ± 0.623.40 ± 0.704.15 ± 0.713.66 ± 0.67
    P0.03NSNSNSNSNS
FMD
    Baseline5.8 ± 2.35.8 ± 2.86.0 ± 3.36.3 ± 2.05.6 ± 2.75.5 ± 3.2
    Exit5.5 ± 3.86.8 ± 2.55.6 ± 3.77.0 ± 3.05.4 ± 3.96.7 ± 2.1
    PNS0.05NSNSNSNS
NID
    Baseline13.4 ± 4.215.7 ± 5.414.4 ± 4.915.5 ± 5.712.9 ± 3.815.8 ± 5.4
    Exit10.2 ± 6.914.9 ± 6.310.3 ± 7.214.6 ± 6.010.1 ± 6.915.1 ± 6.7
    P0.02NSNSNS0.05NS
Ach
    Baseline59 ± 3064 ± 2763 ± 4160 ± 2658 ± 2367 ± 28
    Exit61 ± 3964 ± 3859 ± 4052 ± 3361 ± 4072 ± 40
    PNSNSNSNSNSNS
Sodium nitroprusside
    Baseline34 ± 1839 ± 1840 ± 1741 ± 2131 ± 1838 ± 17
    Exit38 ± 1739 ± 1738 ± 1234 ± 1438 ± 1943 ± 18
    PNSNSNSNSNSNS
  • Data are means ± SD. Data for FMD, NID, and Ach represent percent of increase over baseline. P indicates differences between baseline and exit values.