TABLE 2

Univariate and multivariate logistic regression analyses of factors associated with incident CVD events among type 2 diabetic patients

VariablesUnivariateMultivariate model 1Multivariate model 2Multivariate model 3
NAFLD
    OR1.911.91.841.53
    95% CI1.4–2.21.4–2.21.4–2.11.1–1.7
    P values0.0010.0010.0010.02
ATP III–defined metabolic syndrome
    OR1.641.641.621.58
    95% CI1.3–2.51.3–2.31.3–2.11.3–2
    P values0.0010.0010.0010.01
Age
    OR1.141.131.131.12
    95% CI1.07–1.161.07–1.141.07–1.141.06–1.14
    P values0.0010.0010.0010.001
Sex
    OR1.501.481.461.46
    95% CI1.2–21.2–21.2–1.91.2–1.9
    P values0.0010.0010.0010.001
Diabetes duration
    OR1.08NSNSNS
    95% CI0.8–1.3NSNSNS
    P valuesNSNSNSNS
A1C
    OR1.511.46NSNS
    95% CI1.1–4.91.02–4.2NSNS
    P values0.020.05NSNS
Smoking status
    OR1.441.421.401.40
    95% CI1.1–2.01.1–2.01.1–1.91.1–1.9
    P values0.010.010.010.01
LDL cholesterol
    OR1.18NSNSNS
    95% CI0.9–1.4NSNSNS
    P valuesNSNSNSNS
GGT
    OR1.421.401.27NS
    95% CI1.1–2.01.1–1.91.05–1.7NS
    P values0.0010.0010.01NS
Use of medications
    OR1.0NSNSNS
    95% CI0.7–1.2NSNSNS
    P valuesNSNSNSNS
  • Model 1: adjustment for age and sex; model 2: further adjustment for smoking history, diabetes duration, A1C, LDL cholesterol, GGT levels, and use of medications (i.e., hypoglycemic, antihypertensive, lipid-lowering, or antiplatelet drugs); model 3: additional adjustment for the presence of metabolic syndrome or NAFLD (for the first and second variables in the table) or additional adjustment for the presence of metabolic syndrome and NAFLD (for all other variables in the table).