TABLE 3

Electron transport chain activity in subsarcolemmal and intermyofibrillar mitochondria fractions of human skeletal muscle

LeanObeseType 2 diabetes
n81211
Subsarcolemmal mitochondria fraction0.121 ± 0.0220.034 ± 0.0070.017 ± 0.003*
Intermyofibrillar mitochondria-1 fraction0.130 ± 0.0180.065 ± 0.0140.040 ± 0.008
Intermyofibrillar mitochondria-2 fraction0.138 ± 0.0160.051 ± 0.0080.068 ± 0.008
Total electron transport chain activity0.389 ± 0.0500.150 ± 0.0240.125 ± 0.013
  • Succinate oxidase (units/mU CK).

  • *

    * P < 0.01, type 2 diabetes vs. obese;

  • P < 0.01, type 2 diabetes or obese vs. lean.