TABLE 2

Cytokine production

IFN-γ (pg/ml)Interleukin-10 (pg/ml)
T1DM CD25+0.58 (0.0–175.0)1.6 (1.0–6.5)
T1DM CD25893.7 (221.3–3303)10.3 (6.6–50.0)
T1DM CD25+/CD25379.0 (74.9–3085)*7.1 (2.2–27.8)
Control CD25+0.0 (0.0–15.0)10.1 (0.0–149.0)
Control CD25205.0 (0.0–1572)8.4 (0.0–206)
Control CD25+/CD2541.1 (0.0–358)*29.4 (0.0–81.2)
  • Data are median (range) Cytokine levels from each culture were determined by cytometric bead assay as described in research design and methods.

  • *

    * P < 0.01 comparing results from patients with type 1 diabetes (T1DM) and control subjects.