TABLE 1

Characteristics of subjects investigated

NonfailingDilated cardiomyopathy
Age (years)47 ± 553 ± 11
Sex (M/F)4/17/1
Body surface area (m2)1.81 ± 0.131.83 ± 0.26
New York Heart Association class (III/IV)6/2
Left ventricular end diastolic diameter index (mm/m2)26.1 ± 3.644.1 ± 6.7*
Left ventricular mass index (g/m2)101 ± 16266 ± 49*
Ejection fraction (%)63 ± 3.219 ± 7.5*
Cardiac index (l · m−2 · min−1)2.03 ± 0.40
Mean pulmonary artery pressure (mmHg)22.7 ± 8.6
Left ventricular end diastolic pressure (mmHg)19.4 ± 7.3
Pulmonary capillary wedge pressure (mmHg)14 ± 4
End systolic stress (kdyne/cm2)99 ± 18
End diastolic stress (kdyne/cm2)22 ± 5
  • Data are means ± SE.

  • *

    * P < 0.01 vs. control subjects.