TABLE 3

Prevalence and odds of diabetes at follow-up in quartiles of C3 at baseline

Q1Q2Q3Q4P for trend
C3 (g/l)<0.840.85–0.970.98–1.12>1.12
n755574686687
Diabetes at follow-up (%)1.53.34.28.4<0.0001
Model 11.002.4 (1.1–5.3)2.9 (1.4–6.0)5.6 (2.8–10.9)<0.0001
Model 21.002.2 (1.0–4.7)2.3 (1.1–4.8)3.8 (1.9–7.7)<0.001
Model 31.002.1 (0.83–5.4)2.6 (1.1–6.1)3.3 (1.4–7.8)0.006
Model 41.002.1 (0.80–5.3)2.5 (1.1–6.2)3.2 (1.3–8.0)0.017
  • Data are OR (95% CI), unless otherwise noted. In analysis for models 3 and 4, 1,907 men, 87 with future diabetes, were available. Model 1: Odds ratios adjusted for age, screening year, and glucose at baseline. Model 2: Adjusted as in model 1 plus heredity for diabetes, smoking, triglycerides, blood pressure−lowering medication, BMI, weight increase during follow-up, and physical activity at baseline and follow-up. Model 3: Adjusted as in model 2 plus log HOMA. Model 4: Adjusted as in model 3 plus fibrinogen, haptoglobin, orosomucoid, α1-antitrypsin, ceruloplasmin, and C4.