TABLE 3

Fasting glucose concentration, adjusted for sex, age, and BMI by cohort, by GCK(−30) genotype

BCGPlymouth adultsExeter male subjectsCombined nonpregnant/NGT subjectsExeter pregnant female subjects
GG4.57 (4.54–4.60) (426)4.66 (4.60–4.71) (232)4.69 (4.65–4.73) (508)4.65 (4.63–4.67) (1,166)4.31 (4.28–4.34) (502)
GA4.64 (4.59–4.69) (180)4.74 (4.66–4.82) (111)4.75 (4.69–4.81) (239)4.71 (4.67–4.75) (530)4.39 (4.35–4.43) (226)
AA4.50 (4.35–4.65) (20)4.78 (4.54–5.01) (13)4.76 (4.60–4.95) (34)4.68 (4.58–4.78) (67)4.35 (4.22–4.47) (27)
GG vs. GA (P value)0.040.090.080.0020.003
GG vs. AA (P value)0.330.360.330.570.57
GG vs. A (P value)*0.100.060.070.0030.003
  • Data are means (95% CI) (n). EFS female subjects were pregnant at time of study so were analyzed separately.

  • *

    * GA and AA combined.