TABLE 3

Rates of glucose oxidation, lipid oxidation, and RQ in the basal state and during the euglycemic-hyperinsulinemic clamp in control subjects and patients with type 2 diabetes before and after weight loss

ControlP value, control vs. type 2 diabetes before weight lossType 2 diabetes before weight lossType 2 diabetes after weight lossP value, type 2 diabetes before vs. after weight loss
n1088
Basal glucose oxidation (mg · kg LBM−1 · min−1)1.01 ± 0.13NS1.06 ± 0.260.85 ± 0.13NS
Basal lipid oxidation (mg · kg LBM−1 · min−1)4.60 ± 0.36NS4.03 ± 0.664.63 ± 0.49NS
Basal RQ0.81 ± 0.01NS0.82 ± 0.020.80 ± 0.01NS
Clamp glucose oxidation (mg · kg LBM−1 · min−1)3.05 ± 0.520.0143.85 ± 0.553.06 ± 0.68NS
Clamp lipid oxidation (mg · kg LBM−1 · min−1)0.89 ± 0.21<0.000011.40 ± 0.171.57 ± 0.21NS
Clamp RQ0.93 ± 0.010.0180.85 ± 0.020.87 ± 0.02NS
  • Data are means ± SE. LBM, lean body mass; RQ, respiratory quotient.