TABLE 1

Hormone levels and plasma glucose

After 12 weeks of placeboAfter 12 weeks of DHEAP
DHEA-S (μmol/l)0.8 ± 0.09.5 ± 0.66<0.00001
Total testosterone (nmol/l)0.42 ± 0.211.2 ± 0.23<0.00001
Bioavailable testosterone (%)10.9 ± 0.8712.6 ± 0.960.032
Androstenedione (nmol/l)1.52 ± 0.7112.89 ± 2.33<0.00001
Estradiol (pmol/l)124.8 ± 34.4185.5 ± 33.10.051
Fasting insulin (pmol/l)53 ± 6.5842 ± 4.940.005
Glucagon (pmol/l)195 ± 15.0178 ± 11.320.020
Cortisol (nmol/l)723 ± 86.1667 ± 64.70.361
SHBG (nmol/l)60.2 ± 6.3453.7 ± 6.440.041
IGF-I (nmol/l)32.2 ± 2.8536.5 ± 2.500.058
IGFBP-1 (nmol/l)1.25 ± 0.131.13 ± 0.110.218
IGFBP-3 (nmol/l)167 ± 8.7169 ± 9.70.815
Fasting glucose (mmol/l)4.8 ± 0.114.7 ± 0.100.215
  • Data are means ± SE.