TABLE 3

Cis-regulated genes in DBA blocks of BKS (chromosome 12)

Locus link/ Genbank IDGene symbolFull gene namePhenotype code*Gene locationMorgan locationeQTL locationLogarithm of odds scorer2
Chromosome 12:10.4-84.7Mb
    706195730510P18RikRIKEN cDNA 5730510P18 gene13,254,1300.00013,520,02723.8060.5169669
    14245Lpin1lipin 116,930,9160.060115,536,53822.3300.6045347
    50496E2f6E2F transcription factor 617,204,8400.02017,525,5315.8610.2192264
    71853Txndc7thioredoxin domain containing 717,659,1370.040111,531,03512.7080.4389293
    BE992406UI-M-BZ1-beg-g-08-0-UI.s1 NIH_BMAP_MHI2_S1 Mus musculus cDNA clone19,125,1450.040111,531,0357.3990.3078787
    20135Rrm2ribonucleotide reductase M2hfffa, hfldlv, hftcho, loghfffa, loghftg19,155,6710.080119,542,04213.9280.4947893
    77480C330002I19RikRIKEN cDNA C330002I19 gene19,506,7710.040111,531,03513.1220.4488543
    728772900003A17RikRIKEN cDNA 2900003A17 gene19,509,4950.040111,531,03532.4680.7620641
    15902Idb2inhibitor of DNA binding 219,542,0440.040111,531,0355.0750.206266
    246196Zfp277zinc finger protein 27735,174,5910.140131,558,55428.4580.6095555
    BB347868Dock4RIKEN cDNA clone B930067K06hfffa, loghfffa35,351,6460.165236,577,8188.7530.2576814
    12632Cfl2cofilin 2, muscleloghfhdl50,275,5550.365261,347,57310.3390.4205977
    733851700047I17RikRIKEN cDNA 1700047I17 gene50,466,3050.265248,962,6956.1230.2173526
    24067Srp54signal recognition particle 5450,505,0570.225244,008,7457.5490.2703286
    15375Foxa1forkhead box A152,888,4080.245246,485,7209.5220.4084019
  • *

    * Phenotype code definition: hfffa, Plasma free fatty acid (high-fat diet); hfldlv, Plasma LDL and VLDL cholesterol level (high-fat diet); hftcho, Plasma total cholesterol level (high-fat-diet); logfffa, Log of plasma free fatty acid (high-fat diet); loghfhdl, Log of plasma HDL level (high-fat diet); loghftg, Log of plasma triglyceride level (high-fat diet). A complete Table 3 covering all chromosomes is found in the online appendix.