TABLE 2

General characteristics of South Asians living in Dallas

Nondiabetic subjects
Diabetic subjects
Wild-type ENPP1121Q ENPP1Wild-type ENPP1121Q ENPP1
n (M/F)646 (378/268)316 (187/129)67 (47/20)54 (29/25)
Age (years)43 ± 1442 ± 1456 ± 10*53 ± 129*
BMI (kg/m2)25 ± 425 ± 426 ± 425 ± 4
Systolic BP (mmHg)126 ± 18128 ± 20137 ± 18134 ± 21
Diastolic BP (mmHg)79 ± 1181 ± 1282 ± 1280 ± 12
Total cholesterol (mg/dl)186 ± 38183 ± 35187 ± 43188 ± 34
LDL cholesterol (mg/dl)112 ± 30110 ± 29107 ± 34110 ± 30
HDL cholesterol (mg/dl)45 ± 1145 ± 1142 ± 941 ± 10
Triglycerides (mg/dl)161 ± 122161 ± 110189 ± 127208 ± 116
Fasting glucose (mg/dl)91 ± 1391 ± 13153 ± 57170 ± 58*
HOMA-IR3.1 ± 5.23.5 ± 3.3NANA
  • Data are means ± SD, unless otherwise specified. P values were determined using ANOVA for multiple comparisons of means.

  • *

    * P < 0.05 for mean difference with the subgroup of nondiabetic subjects with wild-type ENPP1.

  • P < 0.05 for mean difference with the subgroup of nondiabetic subjects with ENPP1 K121Q variant.

  • P < 0.05 for mean difference with the subgroup of diabetic subjects with wild-type ENPP1. BP, blood pressure.