TABLE 3

General characteristics of Caucasians living in Dallas

Nondiabetic subjects
Diabetic subjects
Wild-type ENPP1121Q ENPP1Wild-type ENPP1121Q ENPP1
n (M/F)530 (249/282)187 (91/96)86 (61/25)55 (42/13)
Age (years)46 ± 1543 ± 1659 ± 9*58 ± 9*
BMI (kg/m2)26 ± 526 ± 533 ± 7*34 ± 17*
Systolic BP (mmHg)121 ± 17121 ± 14134 ± 17*134 ± 13*
Diastolic BP (mmHg)73 ± 1075 ± 1180 ± 11*80 ± 11
Total cholesterol (mg/dl)187 ± 41182 ± 41185 ± 37184 ± 25
LDL cholesterol (mg/dl)116 ± 37113 ± 36104 ± 3299 ± 29
HDL cholesterol (mg/dl)47 ± 1547 ± 1440 ± 10*43 ± 14
Triglycerides (mg/dl)134 ± 101122 ± 91225 ± 186*206 ± 116*
Fasting glucose (mg/dl)90 ± 989 ± 10176 ± 76*174 ± 71*
HOMA-IR2.7 ± 2.03.1 ± 3.2NANA
  • Data are means ± SD, unless otherwise specified. P values were determined using ANOVA for multiple comparisons of means.

  • *

    * P < 0.05 for mean difference with the subgroup of nondiabetic subjects with wild-type ENPP1.

  • P < 0.05 for mean difference with the subgroup of nondiabetic subjects with ENPP1 K121Q variant. BP, blood pressure.