TABLE 4

General characteristics of nondiabetic Caucasians and South Asians who underwent OGTTs for determination of insulin resistance

Caucasians
South Asians
Wild-type ENPP1121Q ENPP1Wild-type ENPP1121Q ENPP1
n (M/F)108 (42/66)44 (21/23)108 (70/38)45 (29/16)
Age (years)30 ± 827 ± 732 ± 1131 ± 10
BMI (kg/m2)25 ± 625 ± 523 ± 424 ± 3
Systolic BP (mmHg)114 ± 12117 ± 11114 ± 12116 ± 13
Diastolic BP (mmHg)69 ± 1072 ± 1370 ± 1173 ± 9
Total cholesterol (mg/dl)165 ± 36162 ± 39170 ± 35169 ± 32
LDL cholesterol (mg/dl)97 ± 3194 ± 38104 ± 32101 ± 29
HDL cholesterol (mg/dl)49 ± 1450 ± 1343 ± 11*43 ± 11*
Triglycerides (mg/dl)100 ± 8795 ± 56113 ± 86136 ± 89
Fasting glucose (mg/dl)91 ± 891 ± 991 ± 996 ± 8
AUCinsulin (μU · min/ml)9,5598,06611,471*15,750*
  • Data are means ± SD, unless otherwise specified. P values were determined using ANOVA for multiple comparisons of means.

  • *

    * P < 0.05 for mean difference with the subgroup of Caucasians with wild-type ENPP1.

  • P < 0.05 for mean difference with the subgroup of Caucasians with ENPP1 K121Q variant.

  • P < 0.05 for mean difference with the subgroup of South Asians with wild-type ENPP1. BP, blood pressure.