TABLE 1

The frequency of the IL6-174G>C polymorphism in males and females overall and according to age at onset >10 and <10 years of age

FemalesMalesP
A: -174IL6GC frequency in males compared with females overall
    n521609
    G/G183 (35)198 (32.5)
    G/C256 (49)292 (48)
    C/C82 (16)119 (19.5)0.27
B: -174IL6GC frequency in males compared with females diagnosed >10
    n263339
    G/G95 (36)113 (33)
    G/C134 (51)157 (46)
    C/C34 (13)69 (21)0.016
C: -174IL6GC frequency in males compared with females diagnosed <10
    n258270
    G/G88 (34)85 (31)
    G/C122 (47)135 (50)
    C/C48 (19)50 (19)0.78
  • Data are n (%) unless otherwise indicated.