TABLE 1

Body weight at start and end of the study and organ weights after 8 weeks of intervention

Exercise groupAICAR groupUntreated groupLean group
n12121210
Body weight (g)
    Start179.8 ± 3.5179.8 ± 3.2180.7 ± 2.4137.4 ± 2.4
    After 8 weeks395.5 ± 9.8*366.7 ± 8.2368.8 ± 6.6318.3 ± 3.6
Fat content (g)
    Peritesticular8.12 ± 0.318.26 ± 0.327.46 ± 0.622.36 ± 0.08
    Retroperitonal9.71 ± 0.558.97 ± 0.409.34 ± 0.432.06 ± 0.10
Muscles (g)
    Soleus0.24 ± 0.010.24 ± 0.010.24 ± 0.010.27 ± 0.01
    Extensor digitorum longus0.24 ± 0.010.24 ± 0.010.25 ± 0.010.29 ± 0.02
Kidneys (g)1.22 ± 0.031.13 ± 0.021.41 ± 0.021.09 ± 0.01
Heart (g)1.23 ± 0.04*1.14 ± 0.021.13 ± 0.030.96 ± 0.01
Liver (g)15.32 ± 0.7918.44 ± 0.34§16.49 ± 0.6710.68 ± 0.17
Pancreas (g)0.97 ± 0.030.99 ± 0.040.86 ± 0.061.23 ± 0.05
  • Data are means ± SE.

  • *

    * P < 0.05 for the exercise vs. AICAR and untreated groups;

  • P < 0.01 for the lean vs. exercise, AICAR, and untreated groups;

  • P < 0.05 for the untreated vs. AICAR and exercise groups;

  • §

    § P < 0.05 for the AICAR vs. untreated and exercise groups.