TABLE 3

Data related to the hyperinsulinemic-euglycemic clamp

Exercise groupAICAR groupUntreated group
n557
Basal PG30–0 min (mmol/l)6.9 ± 0.1*7.3 ± 0.214.3 ± 0.6
Clamp PG150–180 min (mmol/l)7.6 ± 0.27.4 ± 0.17.8 ± 0.2
Basal PI0 min (pmol/l)243 ± 23314 ± 50160 ± 26
Clamp PI180 min (pmol/l)723 ± 22*817 ± 49588 ± 32
ΔPI (pmol/l)480 ± 43503 ± 74428 ± 25
GIR150–180 min (mg · kg–1 · min–1)9.0 ± 0.511.4 ± 0.46.3 ± 1.2
Basal Ra (mg · kg–1 · min–1)6.0 ± 0.2*6.7 ± 0.37.7 ± 0.3
Clamp Ra (mg · kg–1 · min–1)7.1 ± 0.3*6.0 ± 0.59.5 ± 0.7
ΔRa (mg · kg–1 · min–1)1.1 ± 0.3−0.6 ± 0.61.8 ± 0.8
Basal Rd (mg · kg–1 · min–1)5.9 ± 0.2*6.7 ± 0.37.9 ± 0.2
Clamp Rd (mg · kg–1 · min–1)16.2 ± 0.417.3 ± 0.615.9 ± 0.7
ΔRd (mg · kg–1 · min–1)10.3 ± 0.4*10.6 ± 0.78.0 ± 0.7
  • Data are means ± SE.

  • *

    * P < 0.05 for the exercise vs. untreated groups;

  • P < 0.05 for the AICAR vs. untreated groups. GIR, glucose infusion rate; Ra, rate of glucose appearance (endogenous glucose release); Rd, rate of glucose disappearance.