TABLE 4

AMPK isoform protein levels in red gastrocnemius, white gastrocnemius, and heart muscle fiber

Exercise groupAICAR groupUntreated groupLean group
n7–107–107–107–10
Red gastrocnemius
    α1141.0 ± 9.0*108.4 ± 2.9100.0 ± 10.887.3 ± 9.6
    α289.0 ± 11.792.3 ± 9.3100.0 ± 7.885.4 ± 9.8
    β1126.5 ± 64.3105.1 ± 62.6100.0 ± 42.3133.1 ± 62.8
    β2103.9 ± 18.987.6 ± 13.6100.0 ± 11.394.4 ± 13.6
    γ1119.5 ± 1.9117.0 ± 4.9100.0 ± 10.296.6 ± 8.0
    γ3119.7 ± 33.993.9 ± 16.7100.0 ± 24.6103.4 ± 29.1
White gastrocnemius
    α1160.7 ± 67.1133.2 ± 56.0100.0 ± 29.192.3 ± 39.0
    α2104.7 ± 2.097.3 ± 3.8100.0 ± 1.999.1 ± 8.0
    β1127.8 ± 73.3129.6 ± 67.9100.0 ± 54.6223.8 ± 122.7
    β2127.3 ± 9.1102.0 ± 9.7100.0 ± 13.5131.6 ± 9.2
    γ197.7 ± 41.4109.3 ± 44.8100.0 ± 40.2105.9 ± 43.4
    γ390.1 ± 24.589.3 ± 27.9100.0 ± 23.2120.1 ± 35.0
Cardiac muscles
    α197.6 ± 1.288.7 ± 3.6100.0 ± 3.294.4 ± 2.2
    α294.8 ± 3.295.6 ± 3.7100.0 ± 3.094.6 ± 2.6
    β1100.6 ± 11.9116.7 ± 16.1100.0 ± 8.989.1 ± 10.3
    β287.3 ± 16.296.8 ± 27.4100.0 ± 21.179.8 ± 14.8
  • Data are means ± SE. Protein levels of the different AMPK isoforms are expressed as percentage of control animals.

  • *

    * P < 0.05 for the exercise vs. untreated and AICAR groups.