TABLE 3

Modeling of extrahepatic (visceral) and hepatic contributions to splanchnic cortisol generation at steady state

Arterial cortisoness (nmol/l)*Hepatic cortisoness (nmol/l)Ra cortisol splanchnicss (nmol/min)*Ra cortisol hepaticss (nmol/min)Ra cortisol visceralss (nmol/min)Visceral cortisone extraction rate (nmol/min)§
921004522.622.4−9.7
92924520.824.20
92804518.126.914.5
92674515.229.829.8
92604513.631.438.6
9240459.135.962.8
9220454.540.586.9
92045045111.0
  • Models were calculated using Eq. 8 in which

  • *

    * denotes measured known variable;

  • denotes unmeasured estimated variable;

  • denotes calculated variable.

  • §

    § In addition, visceral cortisone extraction was calculated from Eq. 9.