TABLE 1

Pretreatment (days 1 and 7) age, BMI, serum analyte concentrations, and hematologic indexes in control and diabetic subjects

ControlDiabeticP
Age (years)46.9 ± 10.650.7 ± 10.8NS
Diabetes duration (years)N/A6.7 (1−34)
BMI (kg/m2)26.2 ± 4.931.3 ± 4.3<0.001
Fasting plasma glucose (mmol/l)4.8 ± 0.510.1 ± 3.8<0.001
HbA1c (%)5.3 ± 0.279.2 ± 2.2<0.001
EC-SOD (units/l)32.2 ± 26.985.2 ± 115<0.01
Albumin (g/l)41.6 ± 2.041.3 ± 2.1NS
IBC (μmol/l)54.7 ± 8.157.2 ± 7.3NS
Ferritin (μg/l)127 ± 94.8388 ± 271<0.001
Cu (μmol/l)15.5 ± 2.816.0 ± 2.4NS
Fe (μmol/l)18.0 ± 4.517.3 ± 4.9NS
Zn (μmol/l)12.1 ± 2.112.5 ± 2.2NS
Ca (mmol/l)2.22 ± 0.152.30 ± 0.27NS
Mg (mmol/l)0.81 ± 0.060.75 ± 0.09<0.01
Mn (μmol/l)0.01 ± 0.020.01 ± 0.01NS
Se (μmol/l)1.11 ± 0.201.20 ± 0.25NS
Hb (g/l)152 ± 9.7150 ± 13.2NS
Packed cell volume (%)45.2 ± 2.944.1 ± 3.9NS
Mean corpuscular volume (fl)90.5 ± 3.885.3 ± 4.3<0.001
White blood cells (× 109/l)6.8 ± 2.76.3 ± 1.3NS
Platelets (× 109/l)248 ± 50234 ± 55NS
  • Data are means ± SD or mean (range). There were 20 subjects each in the diabetic and control groups. Concentrations of Cu, Zn, Ca, Mg, Mn, and Se were determined by inductively coupled plasma−mass spectrometry. [Mn]serum was near the minimum detectable concentration. [Mo]serum and [Cr]serum are not included, as their values were at or below the respective minimum detectable concentration values. P values were determined with a one-way ANOVA (two-tailed tests). N/A, not applicable.