TABLE 3

Weighted residuals (i.e., difference between measured and model predicted C-peptide concentration divided by the SD of C-peptide measurement) of model fit to plasma C-peptide experimental data of the hyperglycemic clamps performed in NGT, IGT, and type 2 diabetic adolescents

TimeC-peptide weighted residuals
NGT (n = 30)IGT (n = 22)DM2 (n = 10)
2−0.34 ± 0.36−0.06 ± 0.44−0.08 ± 0.11
40.41 ± 0.380.31 ± 0.380.28 ± 0.58
60.18 ± 0.47−0.04 ± 0.340.14 ± 0.55
8−0.37 ± 0.52−0.41 ± 0.33−0.45 ± 0.34
10−0.16 ± 0.63−0.07 ± 0.390.10 ± 0.57
200.50 ± 0.610.58 ± 0.610.32 ± 0.37
400.15 ± 0.75−0.39 ± 0.75−0.18 ± 0.65
60−0.30 ± 0.59−0.05 ± 0.66−0.21 ± 0.50
80−0.20 ± 0.700.04 ± 0.66−0.10 ± 0.83
100−0.02 ± 0.650.19 ± 0.570.34 ± 0.42
1200.58 ± 0.800.19 ± 0.650.23 ± 0.77
  • Data are means ± SD. The weighted residuals are a quantitative assessment of the goodness-of-fit of the models to the data: a theorically perfect fit should generate weighted residuals with mean of 0 and SD of 1.